a patent-pending breakthrough

The three things sensitive teeth need. In one formula.

87%feel the difference within 7 days

CalmsStrengthensProtects

a patent-pending breakthrough

The three things sensitive teeth need. In one formula.

Three clinically-backed actives, engineered into one daily formula for sensitive teeth.

Calms

Soothes exposed nerves

Strengthens

Rebuilds weakened enamel

Protects

Seals against triggers

87%feel the difference within 7 days

87%

FEEL RESULTS WITHIN 7 DAYS

120+

CLINICALLY BACKED STUDIES

100%

TUBULE COVERAGE, PREVENTING SENSITIVE TRIGGERS

3x

more calcium vs market leader

The reason nothing has worked.

Sensitive teeth need three things, but regular toothpastes only fix a third of the problem.
S3 delivers them all.

Calms + Strengthens + Protects

Sensitivity targets Targets

Regular sensitive brand Regular sensitive brand

CALMS

STRENGTHENS

PROTECTS

Actions delivered

3 of 3

1 of 3

75% do not get complete relief from today's sensitivity products.

S3 Repair Technology™

A breakthrough in sensitive care.

Three actions. One daily toothpaste.

CALMS + STRENGTHENS + PROTECTS

How each action works

CALMS Potassium Nitrate

Soothes sensitive areas of your teeth, bringing daily comfort from hot and cold.

Dr Surina Sehgal BDS @dr.surina.seghal · 159k followers

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STRENGTHENS Nano-hydroxyapatite

Repairs the damaged enamel surface that triggers sensitivity, getting to work from the first brush.

Dr Victoria Sampson BDS, MFDS @drvictoriasampson · 41k followers

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PROTECTS Biomimetic hydroxyapatite

Forms an invisible protective barrier around your tooth surface, providing defence against daily acid wear.

Dr Surina Sehgal BDS @dr.surina.seghal · 159k followers

Follow

S3 Repair Technology™

A breakthrough in sensitive care.

Three actions. One daily toothpaste.

CALMS + STRENGTHENS + PROTECTS

CALMS

Potassium Nitrate

Soothes sensitive areas of your teeth, bringing daily comfort from hot and cold.

Dr Surina Sehgal BDS @dr.surina.seghal · 159k followers

Follow

STRENGTHENS

Nano-hydroxyapatite

Repairs the damaged enamel surface that triggers sensitivity, getting to work from the first brush.

Dr Victoria Sampson BDS, MFDS @drvictoriasampson · 41k followers

Follow

PROTECTS

Biomimetic hydroxyapatite

Forms an invisible protective barrier around your tooth surface, providing defence against daily acid wear.

Dr Surina Sehgal BDS @dr.surina.seghal · 159k followers

Follow

S3 Repair Technology™

A breakthrough in sensitive care.

Three actions. One daily toothpaste.

CALMS + STRENGTHENS + PROTECTS

CALMS

Potassium Nitrate

Soothes sensitive areas of your teeth, bringing daily comfort from hot and cold.

STRENGTHENS

Nano-hydroxyapatite

Repairs the damaged enamel surface that triggers sensitivity, getting to work from the first brush.

PROTECTS

Biomimetic hydroxyapatite

Forms an invisible protective barrier around your tooth surface, providing defence against daily acid wear.

works from the first brush

Results you can see. And feel.

S3 Sensitivity Science™ better repairs microscopic damage vs the market leading sensitive brand.

before and after treatment S3 vs. market-leading toothpaste · before and after treatment

The market
leader

84% sealed

100% sealed

Independently tested at the University of Reading

Dentine tubule coverage after treatment

Market leader 84%

S3 daily 100%

S3 Daily Sensitive Toothpaste

Calms · Strengthens · Protects

Tubules are microscopic channels in the tooth that let fluid reach the nerve — the path a cold or sweet twinge travels. Seal them and the signal has nowhere to go.

¹University of Reading (2026). Scanning electron micrographs of dentine specimens from the leading competitor and S3 Sensitivity Science™.

Created by
the best in the field.

“I recommend S3 to patients for the most complete sensitive care. The multi-mechanism approach addresses what is actually happening in the tooth, and the results reflect that.”

Dr Surina Sehgal

Founding Dentist

Leading UK Dentist

“Most sensitivity toothpastes just mask the problem. S3 goes after the root cause. It calms the pain, while also rebuilding the enamel and laying down a protective layer.”

Dr Victoria Sampson

Founding Dentist

Leading UK Dentist

“Having spent over a decade in the sensitivity category, I have seen first hand how incremental the innovation has been. With S3, I have set out to deliver a step change for patients and consumers.”

Mick Cox

Co-Founder

10+ years at Sensodyne

“S3 Repair Technology™ is the first of its kind. It took over 3 years to develop, but finally we created something that the category has been missing for decades: a genuinely holistic approach to sensitivity.”

Majedeh Mazrai

Founding Scientist

Ex Sensodyne & Aquafresh

Clinically proven

Don't change your habits. Change your toothpaste.

Powered by S3 Repair Technology™
Starts working from the first brush
30 day money-back guarantee

clinically backed ingredients

87% see results in 7 days

30 day money-back guarantee

The right toothpaste can change your life

Exclusively tested, and approved, by people with sensitivity.

"Tried Sensodyne, Pronamel, Regenerate. S3 is the first one that has made a real difference. Cold drinks are no longer something I think twice about."

"After trying everything I didn't expect much but the difference is amazing. Not having to think about my sensitivity every day has made such a difference."

"I always used to put off hygienist appointments because of the pain but S3 has stopped that. She also said my enamel is so much stronger after just 4 weeks!"

"S3 has made such a difference to my life. I have receding gums so my sensitivity is really bad, but S3 has completely solved that! Love the gentle mint flavour too."

Your questions, answered

How is S3 different?

S3 Daily Sensitive Toothpaste is the only toothpaste to contain S3 Repair Technology™, a unique technology that combines the three things that sensitive teeth need – all in a single formula.

Are your ingredients clinically tested?

Yes. The ingredients behind our patent-pending S3 Repair Technology™ have been backed by over 120+ clinical trials and reviews.

How long until I notice the difference?

87% of existing sensitive toothpaste users feel an improvement within 7 days. For some, it can be much quicker. The compounding effect of daily brushing with S3 continues to develop over 2-3 months.

What are the ingredients?

Clinically active ingredients:
Nano-Hydroxyapatite, Biomimetic Hydroxyapatite, Potassium Nitrate, Fluoride, Xylitol.

Full ingredient list:
Glycerin, Sorbitol, Hydrated Silica, Aqua, Hydroxyapatite, Potassium Nitrate, Xylitol, Hydroxyapatite (nano), Sodium Monofluorophosphate ,
Poloxamer 407, Sodium Lauroyl Sarcosinate , Aroma, Xanthan Gum, Potassium Chloride, Cocamidopropyl Betaine, Carageenan, Phenylpropanol, o-Cymen-5-ol,
Decylene Glycol, Sodium Saccharin, Titanium Dioxide, Potassium Hydroxide, Menthol, Anethole, Mentha Piperita Oil, Limonene, Citrus Limon Peel Oil.

What are the long term benefits of S3?

Thanks to S3's remineralising, strengthening and daily protective properties; the daily use toothpaste continues to compound over time to lead to long-term healthier and stronger teeth.

How does the subscription work?

Your subscription is for one single tube of S3 Daily Sensitive Toothpaste (£19.99). Your plan can be paused, rescheduled or cancelled at any time in your account.

By default your frequency will be set to 4 weeks, which can also be amended in your account.

Are you vegan & cruelty free?

Yes, all of our formulations are proudly formulated vegan & cruelty free.

How does the money-back guarantee work?

We're confident that you'll be glad that you've made the switch to S3. If you have not felt the benefits after 21 days of daily brushing, get in touch with the team and we'd be happy to support.