“Most sensitivity toothpastes just mask the problem. S3 goes after the root cause. It calms the pain, while also rebuilding the enamel and laying down a protective layer.”View profile
Forget that you ever had sensitivity.
Developed by experts and backed by dentists. Switch to S3 today and feel less sensitive by next week.
Shop now*Based on an independent third-party study of 52 existing sensitive toothpaste users.
Sensitive toothpastes can be hit or miss. S3 is different.

Calms, strengthens and protects sensitive teeth.
120+ clinical studies support the ingredients in S3.
Most sensitivity toothpastes just mask the problem. S3 goes after the root cause. It calms the pain, while also rebuilding the enamel and laying down a protective layer.

The only triple-active sensitive toothpaste
Sensitive teeth need three things. S3 is the only toothpaste that brings them together into one daily formula.
Results you can see. And feel.
Independently tested at the University of Reading

Dentine tubules are microscopic channels running through the layer beneath your enamel. When they sit open, heat, cold and pressure reach the nerve inside your tooth — the twinge you feel as sensitivity. Sealing them helps block that signal at the surface.
Independently tested at the University of ReadingStop living around the moment. Start living in it.
With S3 you could feel less sensitive in 7 days. Next month? You've forgotten what sensitivity felt like.



Loved by people that used to feel sensitivity
Bought this because it said it was good whitening as well as sensitive. Would say it works great!
In my late seventies still with most of my own teeth, albeit with a history of tooth sensitivity. This new toothpaste has helped with that sensitivity, which during the recent warm spell has been a real blessing. I recommend it to anyone with tooth sensitivity, especially older folks.
Having suffered with sensitive teeth for as long as I can recall, I’ve ran the gamut of brands out there claiming to address the issue. At best, they tend to improve the situation rather than cure it. S3, which I’ve been using for about 6 weeks at time of writing, is in a different league. There was an almost immediate difference in how my teeth reacted to cold drinks, ice cream, etc., and it has only got better and better since then. It’s a strange position to be in now, where my reactions to previous triggers are simply psychological, rather than physical - I’ve got a lot of muscle memory and bad habits to unlearn! For anyone even thinking about trying S3, please do so - it’s no exaggeration to say it could well change your life. It is more expensive than those “sensitive” toothpastes to be found on the supermarket shelves but it worth every single penny. Buy smarter, not cheaper.
I do suffer from mild sensitivity sometimes and I am using S3 since 4 weeks because I was interested in hydroxyapatite toothpaste but didn't want to give up to fluoride. Tbh, the experience so far is WOW. My teeth feel so gentle and I started seeing also a better, whither color on the enamel. Sensitivity is also gone, but I am strongly surprised by the daily compounding effect on the general health of my teeth. Happy subscriber so far!!
Never actually experienced any benefit from sensitive toothpastes until using S3. I was trying Colgate sensitive because Sensodyne did nothing, but that was also pretty poor. As soon as I switched to S3 I was genuinely amazed at the difference!
I'm a 50yr plus mom of 3 living in the UK - that really looks after her teeth, however due to stress I've been clenching my teeth while I sleep which has resulted in my teeth being quite sensitive due to fine hairline cracks that have developed over the years. Despite using a mouth guard at night and using the usual toothpastes recommended by my dentist non have helped. (The likes of Sensodyne and other popular brands caused a burning sensation on my front teeth when I first applied them when brushing (due to the hairline cracks)! A few weeks ago I was on my social media when this advert for S3 toothpaste came up on my feed, and out of desperation I decided to give this toothpaste a go. I am SO happy that I did! I have been using the S3 toothpaste for over 2 weeks now and Honestly - WHAT A DIFFERENCE! I now no longer flinch when I start brushing my teeth as the sensitivity has gone. It's so good that I immediately ordered another and I've just received my second tube a few days ago, as I never want to be without it, and will always have one spare in the cupboard. The peppermint taste is very pleasant and not overpowering and my teeth are not only desensitised but clean and naturally white. (I don't drink wine and generally try and stay away from foods that stain my teeth). I can HIGHLY recommend using the S3 Sensitivity Science. Not only will your teeth feel AMAZING but the customer care and attention to detail is FIRST CLASS! The team genuinely care and have been in touch making sure that the S3 is working for me. What a BRILLIANT company and thank you for developing a toothpaste that WORKS. You have a customer for life! THANK YOU!
Been using it for a couple of months now and i genuinely can’t remember the last time I had sensitivity and my teeth are quite worn down in places. Will be my main toothpaste going forward definitely.
Excellent product. I had been suffering with sensitivity with one of my back teeth due to an exposed nerve. I had tried other branded sensitive toothpastes but nothing really helped. I came across S3 on social media and thought I would try it. I'm so glad that I did, it's really has made a difference. I have just purchased again and will be making this my new regular toothpaste
Excellent toothpaste! Highly recommend.
Fantastic toothpaste, genuinely feel like it's strengthening my teeth
So grateful to have finally found a toothpaste that actually helps with my sensitivity. After a few uses only, the difference on my teeth was noticeable. The S3 website is also very well designed and with thorough information about how the toothpaste works, good pricing and significant savings when subscribing.
Wow this is great- game changing for my sensitive teeth!
The company contacted me before the package arrived today it was on its way, they then wassap me as it arrived and gave me tips and advice, a founder then reaches out on some questions, and then the product started working, have only been using a week and its 100% making a difference, and the customer service is refreshingly, jenuine great people to deal with, with a great product
Great taste and teeth feel great. Had a small problem with my order but they resolved it the next day - can’t ask for anything more
Good quality, definitely felt like my teeth respond to this better then what I've used before
Lucky enough to try pre launch and so impressed with the results. Such a positive impact on my sensitive teeth. Cant wait to get my hands on some more.
I couldn't believe my luck after trying this for 2 weeks to find out that my sensitivity are completely gone. I'm not even joking. I've never found a sensitive toothpaste that actually delivered 100% sensitivity protection to hot and cold. I did find that the original price point of £19.99 was way out of my budget. But my next subscription thankfully was £14.99 which is way more affordable. Based on the research I've done considering the amount of work that they've done to produce this, I think it's a reasonable cost. Although I do think for a toothpaste, it is still overpriced. But I am over the moon with the results and as I can't find anything else that solves my sensitivity as good as this, I'm more than happy to pay it for now. The customer service has been absolutely outstanding. I can't fault them at all. Every time I've emailed them I've had a reply within 24 hours. It's always been a friendly response and very helpful service.
Incredible! I grind my teeth at night and get sensitive to hot things especially. Been using S3 for the last month and have really noticed the diffeerence - no sensitivity at all it’s incredible
I have never found a toothpaste for sensitive teeth that delivers what it promises until now! I have been using S3 for a couple of months and I no longer worry about cold or hot foods and drinks. The results are truly amazing and I promise that is not hyperbole!
So I’ve been using S3 for 3 weeks or so and it’s a revelation. I’d pretty much forgotten about sensitivity and I’d swear my teeth are shinier too. Certainly feel smoother
I've tried many other products for my sensitivity before, and after a while they sort of loose its effect on me. I have been using S3 for a while, and it just keeps working. Being able to drink cold drinks without worrying about it is such a relief.
Recently had a filling done in a back tooth, so my dentist told me to buy a specific toothpaste. didn’t like the smell and was complaining so my girlfriend bought me this one…I have to say it’s not cheap but I’ll buy it again since it does the job and sensitivity overall is much much better. Recommended!
I have always had sensitive teeth and I’ve seen a noticeable difference from the first time I tried S3. It’s a product that I will continue to use. I have caught by the marketing and it’s really exciting to find a product that really lives up to it! Something that will be a staple in my bathroom for years to come!
I thought I’d experiment with new toothpaste after some slight sensitivity and this toothpaste has massively helped. Took a week or so but haven’t had any sensitivity since . Would rather not subscribe but they do a discount
I have some mild sensitivity that comes and goes and I wanted a toothpaste to treat this plus protect them in the future. S3 toothpaste has been great at this, no more sensitivity and it leaves an amazing fresh feeling after using. Would highly recommend.
Fantastic new business and proud to support. The toothpaste is my go to now especially as they have been so sensitive.
Quality feel, nice and fresh
Really pleased with this toothpaste. The consistency is not too thick, so it becomes almost a mouthwash, reaching all the areas of your teeth and mouth, for a deep clean, but in just one step. Flavour is subtle, which I prefer, not overpowering, but still refreshing. Whole mouth feels comfortable and clean immediately after first use. Tooth Sensitivity with sweet and cold foods/ drinks, is greatly improved even from day one, and just getting better and better the longer I use it, 21 days and counting. Teeth feel smoother after use, just like after a dentist polish, but without the abrasion damage. Best value is to buy on a Subscription, a little goes a long way, so still good value for money, for a triple action, sensitivity control toothpaste.
Really impressed with S3 Sensitivity Science toothpaste — gentle, effective and leaves my teeth feeling clean and fresh without aggravating sensitivity. Would definitely recommend.
As someone who has suffered with sensitive teeth for as long as I can remember and has therefore tried every sensitive teeth product out there, I am so, so pleased to have given S3 a go. Genuinely not had these results from any other toothpaste. Excited to continue using and hopefully continue seeing results. If you have sensitive teeth, I can’t recommend giving this a go more.
S3 are a great company to do business with and as a brand new venture I feel great supporting them via my toothpaste subscription. The product does exactly what it is supposed to do and is very pleasant to use. The taste and consistency are both good. Follow up WhatsApp messages are friendly and informative. I'd recommend this toothpaste/company!
I am in my 70’s and suffered with bad teeth all my adult life, especially sensitivity. I haven’t been able to find a sensitive toothpaste that truly works till now- S3 really does what it says on the label. S3 has changed my life re: eating ice cream, cold drinks etc. What a difference in just 2 weeks! It has a refreshing peppermint taste which leaves your mouth feeling clean and fresh after brushing. I will certainly continue to use S3 and will readily recommend the Company to all my family and friends.
Have used Sensodyne for years but tried S3 a few weeks ago after seeing an them on Facebook. So glad I did, my sensitivity has completely gone after a few days - thank you S3!!
Tried S3 as part of the pre launch and have been amazed! No sensitivity at all after about 2 weeks, I couldn't believe it. Have had sensitivity for about 3 years so it's made a real difference. Keep it up!
I’ve struggled with tooth sensitivity my whole life and tried almost every product on the market without finding one that really worked. A friend recommended S3, so I decided to give it a try. Six months in, I can say it’s the best toothpaste I’ve ever used for reducing sensitivity-related pain. Highly recommended.
I have been using this toothpaste for the past 7 weeks, I’ve been struggling with awful sensitivity to warm/hot drinks which has been spoiling my morning coffee. It’s taken 5-6 weeks but it has reduced the sensitivity dramatically! It tastes great. Yes it’s a little expensive but I’ve been miserable and you can’t put a price on my morning coffee!!
As a person with sensitive teeth I’m very attentive of what’s available in the market. I spotted S3 from a product review and I immediately wanted to try. The ingredients are next gen and no other toothpaste features the same formulation.
I’ve sensitive, and for want of a better term rather ‘precious’ teeth where I’ve struggled to find sensitive toothpastes that work - this works for me. Very happy with the S3 experience thus far.
After an initial issue with my order, S3 acted quickly to resolve my problem and even threw in an extra toothpaste to make up for it. Very happy customer, only tried the paste once so far but it seems to work well with an immediately noticeable reduction in sensitivity.
I have had tooth sensitivity for a few years now and my usual toothpaste wasn't helping anymore. I had a dental appt check up and my Dentist assured me everything was ok. I have been using S3 for 9 weeks now and it is amazing the sensitivity has gone-completely!. Ordering S3 was so easy and having the follow up from the team via WhatsApp is great. I would recommend S3 to anyone struggling with tooth sensitivity
Created by sensitivity specialists & dental experts
“I recommend S3 to patients for the most complete sensitive care. The multi-mechanism approach addresses what is actually happening in the tooth, and the results reflect that.”View profile
“S3 Repair Technology™ is the first of its kind. It took over 3 years to develop, but finally we created something that the category has been missing for decades: a genuinely holistic approach to sensitivity.”View profile
“Having spent over a decade in the sensitivity category, I have seen first hand how incremental the innovation has been. With S3, I have set out to deliver a step change for patients and consumers.”View profile
